Cafe Guayasamin - Centro Historico

Ranked twenty-first in South America's best coffee shops for 2025, Cafe Guayasamin has been roasting twice a week and sourcing directly from around twenty-four Ecuadorian farms per year since its founding roughly a decade ago. Beans score above 86 points and rotate every twelve to twenty days, ensuring freshness that few multi-site operations match. The colonial-quarter branch sits at one of the most storied corners in the capital.